RNAseq data analysis from a cohort of NMSC patients (E-MTAB-5678 dataset) revealed increased LGALS7 expression in neoplastic (intraepidermal carcinoma; IEC and squamous cell carcinoma; SCC) and pre-neoplastic (actinic keratosis; AK) lesions compared to normal tissue (Fig. 8A). Here, LGALS7 is linked to actinic keratosis.