INS and type 2 diabetes mellitus: The proinsulin lead variant rs13266210 is in strong LD with the ANK1 eQTL (rs3802315, r2 = 0.84) and the East Asian AGEN T2D lead variant (rs62508166, r2 = 0.92), and HyPrColoc shows strong evidence of colocalization across all three studies (PPFC = 0.92).