Commercial digital biosensor chips consistingof GFETs have been developed recently and are now available in themarket for selective detection of biomarkers related to inflammation,autoimmune disease, and biomarkers such as human interleukin-6 (anti-IL6)and recombinant human IL-6 (IL6) in late-stage cancer patients (Figure 6I,J).43 In these devices, anti-IL6 is immobilized ona carboxyl functionalized graphene surface via standard carbodiimidecross-linker chemistry. This evidence concerns the gene IL6 and autoimmune disease.