NEFL and dementia: Although very limited research exists regarding factors associated with dementia-related blood biomarkers, kidney function has also been shown in several studies to be associated with biomarker levels and has been named a research priority in recent recommendations by the Alzheimer’s Association on the appropriate use of blood biomarkers.9 Reduced kidney function has been associated with increased levels of neurofilament light (NfL),10,11,12 phosphorylated tau (p-tau),12,13 total tau,10 and amyloid-β in blood.10