METTL3 and acute myeloid leukemia: Retransplantation experiments in rodents using murineor patient-derived AML cells from primary transplants treated witha vehicle or compound 3b demonstrated a prolongationof survival and an evident decrease of AML cells in peripheral bloodfollowing 3b treatment.132 These experiments highlight the effect of the pharmacological inhibitionof METTL3 in AML, especially in preventing or prolonging the diseaseafter transplantation.