The RNA writer METTL3–METTL14affects the RNA metabolismdirectly or indirectly, thus impacting its downstream processing.As a result of aberrant METTL3–METTL14-mediated RNA methylation,irregular cellular processes, as outlined above, might have severeimplications for the onset and/or progression of various diseasessuch as viral infections, cardiovascular pathologies, neurologic disorders,and cancer. The gene discussed is METTL14; the disease is cancer.