For example, variants rs12579302, rs10886430, rs55983834, rs2501966, rs12426667 are stroke risk loci in differentially expressed stroke outcome genes ATP2B, GRK5, SH3PXD2A, CENPQ, HOXC4, respectively; and intergenic variants rs2107595 and rs1487504 are stroke risk loci in differentially expressed outcome genes HDAC9 and BNC2, respectively [55]. The gene discussed is GRK5; the disease is stroke disorder.