As shown in Fig. 6a–d, VIRMA knockdown (HuCCT1-shVIRMA) led to significantly low tumor growth rate and tumor weight compared with the other groups (HuCCT1: 0.75 ± 0.05 g, HuCCT1-shNC: 0.77 ± 0.02 g, HuCCT1-shVIRMA: 0.28 ± 0.01 g). The gene discussed is VIRMA; the disease is neoplasm.