By constructing ZNF267 overexpression and knockdown CRC cell lines (Fig. 4A-D, S3A [see Additional file 2]), we performed transwell assays and found that ZNF267 overexpression inhibited CRC cells migration and invasion (Fig. 4E, G), while ZNF267 interference obtained opposite results (Fig. 4F, H). Here, ZNF267 is linked to colorectal carcinoma.