Moreover, among the enriched genes in the group of cancer areas in the dHGP, we detected many genes known to enhance inflammatory reactions in cancer by promoting the NFκB pathway (IKBKB, FKBP4 [36]), activating lymphocytes (TNFSF9, HLA-F) [37, 38] or recruiting neutrophils (DPEP1) [39] (Fig. 2h). Here, HLA-F is linked to cancer.