CA1 and colorectal carcinoma: Carbonic anhydrase-1 (CA1, 8q21.2) is reported to be decreased in CRC [40], which is consistent with our results (RNA: log2FCTvsNM = − 4.02, q-value = 0.0068; log2FCLMvsNM = − 4.12, q-value = 0.0057, protein: log2FCTvsNM = − 21.01, q-value = 0.0029; log2FCLMvsNM = − 20.88, q-value = 0.0029).