CTH and diabetes mellitus: Cystathionine gamma-lyase (Cth or CSE) is an enzyme that can break down cystathionine into cysteine, alpha-ketobutyric and ammonia, which are intermediate metabolites that eventually catalyse the synthesis of gases such as H2S. It has been reported that the amount of H2S is associated with diseases such as hypertension, diabetes, acute pancreatitis and haemorrhagic shock [11, 12].