Studies have shown that RELMβ is abundantly expressed in gastric carcinoma cells, and over-expression of RELMβ can promote the invasion and migration of gastric carcinoma cells via facilitating EMT, as evidenced by EMT-related proteins, such as up-regulation of N-cadherin, Snail, Vimentin and down-regulation of E-cadherin [110]. This evidence concerns the gene CDH1 and gastric carcinoma.