A large number of studies have shown that RELMβ is expressed in goblet cells, pulmonary arteries smooth muscle cells (PASMCs), human umbilical vein endothelial cells (UVECs), human pulmonary artery endothelial cells (PAECs) and colon cancer cells, etc. [28, 30–32]. Here, RETNLB is linked to colonic neoplasm.