For high-risk patients, the factors associated with both DFS and OS were tumor location, tumor diameter, Ki-67 index, and TKI treatment methods, and all P were less than 0.001, all of which were independent risk factors affecting prognosis; but except for In addition to the above factors, surgical method was associated with postoperative DFS (P < 0.001), while mitotic figures were associated with postoperative OS (P < 0.001). This evidence concerns the gene MKI67 and neoplasm.