The results are as follows: (1) among intermediate risk, patients with the impact of Independent factors associated with DFS included tumor location (P < 0.001) and KI-67 index (P = 0.008), but only postoperative TKI treatment was associated with postoperative overall survival (P < 0.001), and irregular targeted therapy of intermediate-risk patients was associated with poorer prognosis (HR 1.95, 95% CI 1.31–2.49, P < 0.001). The gene discussed is MKI67; the disease is neoplasm.