How l-fuc may regulate these signaling pathways and enrich for CD4+ T memory subsets within the tumor microenvironment and, furthermore, how l-fuc alters DC biology and induces their intratumoral accumulation (Figs. 2 and 5) may contribute to anti-tumor immune responses and tumor suppression in this context are unclear and warrant further lines of study. The gene discussed is CD4; the disease is neoplasm.