HLA-DRB1 and neoplasm: To assess how HLA-DRB1 glycosylation–fucosylation contributes to tumor suppression and itICs, we compared control- or EB1-knocked-down SW1 tumors reconstituted with WT or glycofucomutant (N46G) EB1 (confirmation of knockdown reconstitution and fucosylation by IB and LPD, respectively, in Extended Data Fig. 5e).