CD4 and neoplasm: Intriguingly, oral l-fuc induced significant, albeit transient, increases in intratumoral monocyte-derived DCs (moDCs) and lymph node conventional DC2 (cDC2) cells, which can promote memory CD4+ T cell phenotypes and cross-talk with CD4+ T cells to mediate tumor suppression, respectively18–20 (Fig. 2a,c (orange dashed boxes) and Supplementary Table 1).