POMC and neoplasm: In light of the recurrent nature of the EWSR1::BEND2 fusions (detected in two of our cases and in the one ACTH-positive tumor in the Scarpa et al. study [17]), it seems that these fusions are likely driver events in these tumors as they proved to be mutually exclusive with ATRX, DAXX, and MEN1 mutations (as the most frequently mutated genes in NETs) in all four fusion-positive cases.