Among 23 tissue RET fusion positive patients [20 (lung adenocarcinoma/NSCLC/lung cancer-NOS), 2 (carcinoma of unknown primary), 1 (prostatic adenocarcinoma)] with both tissue and liquid NGS, 14 (61%) patients had RET fusion detected on liquid assay. The gene discussed is RET; the disease is non-small cell lung carcinoma.