Li H et al. [54] have shown that ApoC-III directly promotes the expression and activation of the vascular cell adhesion molecule-1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs) and induces monocyte adhesion with an increase of inflammatory response and an important contribute to atherosclerosis progression. The gene discussed is APOC3; the disease is atherosclerosis.