APOC3 and hypertriglyceridemia: In vivo studies performed in mice and humans have reported that ApoC-III plasma levels are increased by post prandial (PP) free fatty acids [43], and recently, Guan Y et al. have performed a study to investigate possible correlations between ApoC-III and PPL [44]: they have found that subjects with PP hypertriglyceridemia (PPT) have both fasting and PP elevated levels of ApoC-III, which represents an independent risk factor of PPT as well as a causative factor and may be considered a possible biomarker of PPT itself.