Recently, Sigfrids FJ et al. have performed a study including 3966 subjects with type 1 diabetes to evaluate a predictive role of ApoC-III in diabetic kidney disease (DKD), major adverse cardiac events (MACE), and mortality: it was reported a positive correlation between ApoC-III and cardiovascular events in type 1 diabetic presenting with albuminuria, thus predicting DKD progression and mortality [60•]. Here, APOC3 is linked to diabetic kidney disease.