Regarding the kinases, we found that elevated activity of MAP3K8 and PRKCA was associated with less probability of survival in renal cancer (MAP3K8: HR = 10.5 (95% CI 5.81–19), adjusted P‐value = 1.1e‐13; PRKCA: HR = 6.15 (95% CI 4.27–8.84), adjusted P‐value = 2.3e‐21; Fig 4E and F). The gene discussed is MAP3K8; the disease is renal carcinoma.