Though the database may not have been powered enough to fully elucidate the combined influence of OSA and the presence of APOE-e4 allele on biomarkers of AD across Black/African American and White participants, the results of these analyses indicate that there is a possibility, that it may exert different influences in different populations, and galvanizes the need for further research. This evidence concerns the gene APOE and obstructive sleep apnea syndrome.