These keywords, which included exosome, microglial polarization, pet imaging, CSF1R, synaptic pruning, glycolysis, microglial heterogeneity, and gender differences, were discovered to be primarily concentrated in cluster 1/2/5/6, with a focus on human, chronic stress, aging, neurodegenerative diseases, and nerve regeneration (Table 4, keywords B). The gene discussed is CSF1R; the disease is neurodegenerative disease.