HGFAC and medulloblastoma: To conduct an unbiased investigation of the mechanism by which SI-CSC medulloblastomas continue to grow in the presence of SMOis, we performed RNA-seq analyses of matched control- and LDE225-treated FSmoM2;hGFAP-cre SI-CSC medulloblastomas (Supplementary Fig. S2B; Supplementary Table S6).