The data show that GSTO2 over-expression in colon cancer is related to age (OR = 2.73 for ≤ 65 vs. > 65), stage (OR = 0.37 for Stage IV vs. Stage I; OR = 0.44 for Stage III vs. Stage I; and OR = 0.6 for Stage III vs. Stage II), M classification (OR = 0.55 for M1 vs. M0), and N classification (OR = 0.57 for N2 vs. N0 and OR = 0.50 for N1 vs. N0) (all p < 0.05) is significantly correlated (Table S4). The gene discussed is GSTO2; the disease is malignant colon neoplasm.