Of note, the study of Cortellini et al. suggested that previous palliative RT was significantly associated with shortened PFS and OS (p < 0.05 for all) in metastatic NSCLC patients with PD-L1 expression ≥50% [20], indicating that the RT types and PD-L1 level may affect the survival outcomes. Here, CD274 is linked to non-small cell lung carcinoma.