The results showed that gender (OR = 2.371), age (OR = 3.646), weight loss (OR = 11.945), reduced food intake (OR = 27.888), serum albumin expression (OR = 2.936) were risk factors for malnutrition in patients with CKD, and the difference was statistically significant (P < 0.05) (Table 4). This evidence concerns the gene ALB and malnutrition.