Based on previous studies and the comparison between MG patients and healthy controls, it is speculated that the change in intestinal microbiota composition may lead to the lack or dysfunction of CD4 + FoxP3+ T cells induced by intestinal bacteria, which has a profound impact on immunity (Kwon et al., 2010; Chae et al., 2012). The gene discussed is FOXP3; the disease is myasthenia gravis.