MME and Sepsis: Therefore, this study will investigate whether CD10 can represent a valid marker for distinguishing mature neutrophil subgroups from immature neutrophil subgroups in LND and NDN under septic conditions; if so, we will continue to use CD10 to isolate and purify mature and immature neutrophils subgroups in sepsis patients’ LDN and NDN, and to study its immunomodulatory effects on lymphocytes.