The concentrations of ZnT3, Dyn1 and GluA3 were significantly elevated in the CSF of Alzheimer’s disease patients compared with the age and gender matched control group (P = 0.003 for ZnT3, P = 0.007 for Dyn1 and P < 0.001 for GluA3, Table 1, Fig. 1A–C). The gene discussed is GRIA3; the disease is Alzheimer disease.