By assessing profibrogenic factors in infarcted myocardial tissue, we found that TGFβ1, CTGF, and TIMP1 expression in the myocardium of the rats with MI treated with the Luhong formula was substantially downregulated, and all three of these factors could promote fibroblast activation [31–34]. Here, TGFB1 is linked to myocardial infarction.