The fusion genes involving NIPBL have been reported in acute megakaryoblastic leukemia (NIPBL-HOXB9) (17) and atypical tenosynovial giant cell tumor (NIPBL-ERG) (18), and it is considered that the NIPBL promoter may contribute to changes in the expression of fusion partners (18). This evidence concerns the gene HOXB9 and acute megakaryoblastic leukemia.