ALK and cancer: We used 4 murine cell lines derived from the C57BL/6 strain: Lewis lung carcinoma (LLC; originally derived from a spontaneous cancer that harbors a KrasG12C mutation (28)), CMT167 cells (derived from a spontaneous cancer that harbors a KrasG12V mutation (29)), and two cell lines derived from tumors induced by injection of an Adeno-cre virus inducing Eml4-Alk translocation (21) (EA1/EA2).