Positive correlations between higher levels of IGF2BP1-3 and C1, C2 and C6 infiltrates suggests that IGF2BPs may have a tumor promoter role, as patients belonging to those immune infiltrates subtypes had worse survival characterized with higher proliferation rate and enriched with TGFβ (Figure 5A and Figure S3). This evidence concerns the gene TGFB1 and neoplasm.