BAX and colonic neoplasm: A newly developed curcumin-like compound (2E,6E)-2,6-bis(2,3-dimethoxy benzyl aniline)cyclohexanone (DMCH) in colon cancer HT29 and SW620 cell lines Analysis of the apoptotic panel of the group showed that Bax protein expression was up-regulated, and it was found that more apoptotic cells were observed in the treated SW620 cell line than in the HT29 cell line (19).