Tumor-supporting activity mediated by macrophage SRs includes regulation of tumor invasion, proliferation and migration (for CD204, CD206, CXCL16, Stabilin-1, and RAGE), as well as M2-like TAM polarization (for CD36, LOX-1, CXCL16, CD 163, and RAGE) and tumor angiogenesis (for CD68, Dectin-1, RAGE). The gene discussed is MRC1; the disease is neoplasm.