Contribution of intracellular sorting function of stabilin-1 to tumor progression is linked to the ability of the extracellular domains of stabilin-1 to interact with at least two human chitinase-like proteins, SI-CLP and YKL-39, while the interaction with true chitinases CHIT1 and AMCase and with YKL-40 was not studied to date (6, 141, 151, 152). The gene discussed is STAB1; the disease is neoplasm.