Transcriptomic analysis of non-small cell lung cancer (NSCLC) samples showed that MARCO expression significantly correlated with gene expression of immunosuppressive TAM-related genes (CD163, MSR1, IL4R, CHIA, TGFB1, and IL10), genes involved in T-cell regulation (FOXP3, TGFB1, IL10, EBI3, PDCD1, and CTLA4) and genes encoding immune checkpoint molecules (PD-L1, PD-L1, VISTA, PD-1, and CTLA4) (30). Here, IL4R is linked to non-small cell lung carcinoma.