PTPN1 and cancer: Herein, within the whole network, 51 edge betweenness was within the RET and diosgenin interaction, 38 with PTP1B and diosgenin interaction, 19 with adherens junction interaction with PTPN1, and central carbon metabolism in cancer interaction with RET, 18 with steroid hormone biosynthesis with diosgenin, and 14 with pathways in cancer with RET (Supplementary File S3; Supplementary Sheet S2).