Moreover, the decreased level of CXCR3 in different identified T cell subsets (i.e., C03, C21, and C27), B cell subsets (i.e., C01 and C05), and myeloid cell subsets (i.e., C06, C07, C08, and C09) consistently showed a negative correlation with the level of TP, HAS, BUN, CRE, while positively related with the ratio of urine trace albumin and creatinine (UTA/CRE), urine transferrin and creatinine (UTF/CRE), and UIG/CRE in the T2D-DN subjects. Here, CXCR3 is linked to liver dysplastic nodule.