Glucagon response was differentiated for early (0-30 minutes), late (30-120 minutes) for OGTT. Authors observed an association for the early lack of response and not the late or total glucagon in participants with prediabetes. In NGT Glucagon-level after OGTT steadily declined and reached its lowest level at 60 minutes of OGTT before returning to baseline at around 120 minutes. This evidence concerns the gene GCG and prediabetes syndrome.