⇑ Plasma asprosin in T2DM females than in healthy subjects⇑ Plasma asprosin in PCOS subjects than in healthy subjects but lower than in T2DM subjects.Plasma asprosin showed positively correlated with FBG, HbA1c, HOMA-IR, LDL-c, Apolipoprotein B (APOB), APOE, and testosterone. The gene discussed is APOB; the disease is type 2 diabetes mellitus.