The involvement of PI3K/Akt/mTOR, PI3K/PTEN/Akt/FOXO3, and Hippo/YAP pathways were reported in both the pathophysiology of endometriosis and the physiological ovarian aging, uncovering its role in bridging OMA and ovarian aging (39–41, 55–57). This evidence concerns the gene AKT1 and endometriosis.