The results showed that eight pathways were identified as the main pathways, including pathways in cancer, fluid shear stress and atherosclerosis, AGE-RAGE signaling pathway in diabetic complications, proteoglycans in cancer, NAFLD, Chagas disease (American trypanosomiasis), HIF-1 signaling pathway, and TNF signaling pathway. The gene discussed is RENBP; the disease is atherosclerosis.