IL10 and pancreatic neoplasm: Moreover, qRT-PCR showed that the expression of the proinflammatory factor IL-10 also increased to some extent after the addition of OST; however, it has also been reported in the literature that OST can attenuate the infiltration of M2 macrophages around pancreatic cancer tumors to inhibit the progression [30], which may be attributed to the fact that the inflammatory microenvironment is fundamentally different from the tumor microenvironment, and a different microenvironment leads to very different changes in macrophages.