The results of KEGG showed that the differential metabolites in seminal plasma of the two pig breeds are mainly involved in the following metabolic pathways: metabolic pathways, ABC transporters, galactose metabolism, carbon metabolism, central carbon metabolism in cancer, citrate cycle (TCA cycle), alanine, aspartate, and glutamate metabolism, lysine degradation, glyoxylate and dicarboxylate metabolism, glucagon signaling pathway, fructose and mannose metabolism, taste transduction, Insulin resistance, amino sugar and nucleotide sugar metabolism (Figure 4C). The gene discussed is ABCG2; the disease is Insulin resistance.