Recently, the survival association of XRCC1 SNPs and XRCC1 protein expression have been reported in various human malignant tumors such as thyroid cancer (Liu and Xue, 2020), lung cancer (Schneider et al., 2008), breast cancer (Sanjari Moghaddam et al., 2016), gallbladder cancer (Wu et al., 2020), and hepatocellular carcinoma (Naguib et al., 2020). Here, XRCC1 is linked to gallbladder cancer.