Thereinto, IGSF10 levels were downregulated in Adrenocortical carcinoma (ACC), BLCA, BRCA, Cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), COAD, ESCA, HNSC, KICH, KIRC, KIRP, LIHC, LUAD, LUSC, Ovarian serous cystadenocarcinoma (OV), PRAD, READ, Skin cutaneous melanoma (SKCM), STAD, Testicular germ cell tumors (TGCT), THCA, and UCEC. This evidence concerns the gene IGSF10 and testicular germ cell tumor.