PFKFB3 and cancer: It was found that LncRNAs can also control cancer cell metabolism, viz., lncRNA YIYA regulates CDK6 (cell division protein kinase 6) dependent phosphorylation of PFKFB3 (fructose bis-phosphatase PFK2), and thus can convert glucose 6-phosphate (G6P) to fructose-2,6-phosphate (Jiang R. et al., 2018).