In general, SDHB mutations have been associated primarily with PCC-type tumors (Ricketts et al., 2010); however, PGLs have previously been described as the primary tumor type diagnosed in cases with exon 1 deletion in the SDHB gene (Astuti et al., 2001; Cascón et al., 2006; Cascon et al., 2007). Here, SDHB is linked to neoplasm.