In our study, we used a large multigene panel that allows the analysis of 105 known cancer susceptibility genes (and candidate genes), including MAX, NF1, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, TMEM127, VHL, FH and MEN1 associated with PGL/PCC predisposition. The gene discussed is SDHB; the disease is cancer.