Finally, none of the sporadic cases reported a family history of PGL/PCC tumors, although 75% of them had a positive family history for other tumors types; while in cases with the CNV in SDHB, 42.9% reported a positive family history of PPGL tumors and another 42.9% had a positive family history for other tumor types (Table 3). Here, SDHB is linked to neoplasm.