In our study, we used a large multigene panel that allows the analysis of 105 known cancer susceptibility genes (and candidate genes), including MAX, NF1, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, TMEM127, VHL, FH and MEN1 associated with PGL/PCC predisposition. This evidence concerns the gene TMEM127 and cancer.