SDHB and adrenal gland pheochromocytoma: It is noteworthy that among the nine cases with a SDHB mutation, only one corresponded to a nonsense variant SDHB: c.268C>T (p.Arg90*), while the remaining eight are carriers of a recurrent CNV consisting of a large deletion of one copy of exon 1, explaining 80% (8/10) of the hereditary PGL/PCC cases and 42% (8/19) of all the cases affected with PGL or PCC tumors (Table 2; Figure 1).