HIF-1, NF-κB, IL-17, EGFR, MAPK, endocrine resistance, tyrosine kinase resistance, platinum drug resistance, antifolate resistance, arginine biosynthesis, sphingolipid, human cytomegalovirus infection, Kaposi’s sarcoma, small cell lung cancer etc. This evidence concerns the gene NFKB1 and Kaposi's sarcoma.