In the cytokine response mediated by tumor necrosis factor receptor 2 (TNFR2) non-canonical nuclear factor kappa B (NFκB) pathway, we found DE mRNAs exclusively in Li-infected macrophages, such as NFKB2 and RelB (Figure 3E) but also DE mRNAs shared by all the three Leishmania species infection, such as TNF Superfamily Member 14 and 15 (TNFSF14/15) and TNF receptor Superfamily Member 1B, 9, 12A and 14 (TNFRSF). The gene discussed is TNFRSF1B; the disease is infection.