HBB and thalassemia: Subjects HFY07, HFY21, and HFY47 had no thalassemia variants but other SNVs detected in their HBB genes by CATSA; HFY07 and HFY21 harbored HBB:c.315+308delA heterozygote; and HFY47 harbored HBB:c.315+337A>G heterozygote (Figures 4A,C,E).