For example, α-thalassemia usually results from NC_000016.10:g.165401_184701del (--SEA), NG_000006.1:g.34247_38050del (-α3.7), NC_000016.10:g.169818_174075del (-α4.2), HBA2:c.427T>C (Hb Constant Spring), HBA2:c.377T>C (Hb Quong Sze), and HBA2:c.369C>G (Hb Westmead) that mainly impair the coding regions of α-globin genes. Here, GSTM1 is linked to thalassemia.