Finally, PFI analysis showed that TGM3 acted as a risk factor for KIPAN, KIRC, ACC, KICH, and CHOL but a protective factor for PAAD and PRAD, which indicated that TGM3 may play a protective role in PAAD and PRAD with regard to prognosis (Figure 2D). Here, TGM3 is linked to prostate adenocarcinoma.