AKT1 and human papilloma virus infection: Figure 4A highlights the most significantly enriched GO terms of the PCGs. The top three were extracellular matrix structural constituents, collagen binding, and integrin binding. After KEGG analysis, we found that the MAPK signaling pathway, the PI3K-Akt signaling pathway, and human papillomavirus infection were the most three enriched pathways (Figure 4B).